Newmarket Scientific Product Search Results for CalRexin(TM)488

Product Search Results: CalRexin(TM)488
Num Products Matched:
Product Search Results: CalRexin(TM)488	Num Products Matched: 2	2

Apop Biosciences

AP-CR488-25

50uL (25 assays)

£138.00

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Product Detail:	Mouse Anti-Human Calcitonin Receptor CalRexin (TM):488 imaging reagent for apoptosis detection
Background Info:	Apop's suite of CalRexin (TM) imaging reagents have been designed for imaging stressed, dying and apoptotic cells. They are monoclonal antibody fluorophore conjugates that target an epitope in the extracellular domain of the human calcitonin receptor (CT receptor), a novel marker of cell stress/autophagy and pre-apoptotic cell stress/apoptosis. They recognise and bind an epitope that is common to both C1a and C1b isoforms of the human calcitonin receptor, a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. The calcitonin receptor has been identified in a broad range of tissues throughout the life cycle of an organism as well as in diseased, stressed and damaged tissues. CalRexin (TM):fluorophore is accumulated into live cells and is designed for live cell assays. Advantages: Simple to use High sensitivity, detect sub-populations in FACS of dying cells Enhanced stability (> 1 yr) Multiple applications (FACS, Operetta, confocal microscopy) Calcium independence for assays No false positives vs Annexin
Product Type:	Antibody
Antibody Type:	Monoclonal
Format:	200 µg in 200 µL PBS Purified, 1 mg/mL in phosphate buffered saline (PBS), sterile filtered
Host Animal:	Mouse
Species Reactivity:	Human cells and cell lines
Immunogen:	Synthetic peptide derived from sequence situated in the N-terminal domain of human calcitonin receptor.
Applications:	Flow Cytometry \| Immunocytochemistry Live* \| ELISA \| Immunoblotting
Clone number:	46/08-2C4-2-2-4
Antibody Isotype:	IgG1
Application Details:	For use in live cell assays to study pre-apoptotic stress and events leading to apoptosis. Flow Cytometry (1:500) Immunocytochemistry Live* (1:500) *Note that cells undergoing programmed cell death must be unfixed during the stain but may be fixed thereafter. ELISA (1:5000/50% colour) Immunoblotting (1:100)
UK:	138
WEBLIST PRICE 2022 USD:	200
GBP Equivalent price at 1.3:	110
Distributor_Net_Purchase_Price_2022_USD:	140
Price to us in GBP:	77.00
Profit:	61.00
Alternative Names:	Monoclonal antibody mAb2C4 conjugated with TFP esters:AZ488 The name given to mAb2C4 is CalRexin (TM)
Shelf Life:	Short term storage (12 months) at 4-6?C
Storage:	Storage for 12 months at 4-6?C after filter sterilization. Do not freeze. Prepare working dilutions on day of use.
Cross Reactivity:	Mouse, other species not tested.
Target:	CALCITONIN RECEPTOR
Research Areas:	Programmed cell death \| Apoptosis

Apop Biosciences

AP-CR488-100

200uL (100 assays)

£516.00

Please sign in or sign up to order this product online.

Product Detail:	Mouse Anti-Human Calcitonin Receptor CalRexin (TM):488 imaging reagent for apoptosis detection
Background Info:	Apop's suite of CalRexin (TM) imaging reagents have been designed for imaging stressed, dying and apoptotic cells. They are monoclonal antibody fluorophore conjugates that target an epitope in the extracellular domain of the human calcitonin receptor (CT receptor), a novel marker of cell stress/autophagy and pre-apoptotic cell stress/apoptosis. They recognise and bind an epitope that is common to both C1a and C1b isoforms of the human calcitonin receptor, a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. The calcitonin receptor has been identified in a broad range of tissues throughout the life cycle of an organism as well as in diseased, stressed and damaged tissues. CalRexin (TM):fluorophore is accumulated into live cells and is designed for live cell assays. Advantages: Simple to use High sensitivity, detect sub-populations in FACS of dying cells Enhanced stability (> 1 yr) Multiple applications (FACS, Operetta, confocal microscopy) Calcium independence for assays No false positives vs Annexin
Product Type:	Antibody
Antibody Type:	Monoclonal
Format:	200 µg in 200 µL PBS Purified, 1 mg/mL in phosphate buffered saline (PBS), sterile filtered
Host Animal:	Mouse
Species Reactivity:	Human cells and cell lines
Immunogen:	Synthetic peptide derived from sequence situated in the N-terminal domain of human calcitonin receptor.
Applications:	Flow Cytometry \| Immunocytochemistry Live* \| ELISA \| Immunoblotting
Clone number:	46/08-2C4-2-2-4
Antibody Isotype:	IgG1
Application Details:	For use in live cell assays to study pre-apoptotic stress and events leading to apoptosis. Flow Cytometry (1:500) Immunocytochemistry Live* (1:500) *Note that cells undergoing programmed cell death must be unfixed during the stain but may be fixed thereafter. ELISA (1:5000/50% colour) Immunoblotting (1:100)
UK:	516
WEBLIST PRICE 2022 USD:	750
GBP Equivalent price at 1.3:	413
Distributor_Net_Purchase_Price_2022_USD:	525
Price to us in GBP:	288.75
Profit:	227.25
Alternative Names:	Monoclonal antibody mAb2C4 conjugated with TFP esters:AZ488 The name given to mAb2C4 is CalRexin (TM)
Shelf Life:	Short term storage (12 months) at 4-6?C
Storage:	Storage for 12 months at 4-6?C after filter sterilization. Do not freeze. Prepare working dilutions on day of use.
Cross Reactivity:	Mouse, other species not tested.
Target:	CALCITONIN RECEPTOR
Research Areas:	Programmed cell death \| Apoptosis

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Product Search Results: CalRexin(TM)488

Product Search Results: CalRexin(TM)488

Anti Calcitonin Receptor - CalRexin (TM):488 Sampler

Anti Calcitonin Receptor - CalRexin (TM):488