Molecular Biology


PCR & qPCR Super Mixes, DNA markers, Ethidium alternatives, NGS library prep kits and more


Our molecular biology range includes NGS Library Prep Kits PCR supermixes, DNA LaddersNucleic Acid Stains, PCR Teaching kits and more

 


OnePCR



Ethidium Bromide Alternative: Novel Juice - Free Samples

Novel Juice is a non-mutagenic alternative to Ethidium Bromide (independent testing report) that is used in the same way as ethidium bromide. It fluoresces brightly under Blue Light or UV and contains three tracking dyes (Bromophenol Blue, Xylene Cyanol FF, and Orange G). It is stable at room temerature for at least 12 months. Free samples available.

 

1ml of 6x solution (Cat No LD001-1000) - £35

10ml of 6x solution (Cat No LD001-1000x10) - £300  

DATASHEET available here

 




T3â„¢ Max Conjugation Kits for Targeted siRNA Delivery

 

The T3™ Max Conjugation Kit is based on Bioo Scientific's Targeted Transport Technology and allows you to target the delivery of siRNA into any cell type (in vivo or in vitro) by conjugating the T3 carrier to an antibody that is specific to a receptor or other extracellular domain specific to the cell or tissue you want to target. 

 

>> Offers targeted in vivo or in vitro delivery of siRNA or miRNA
>> Can be used to target almost any cell or tissue type
>> Flexible - works with multiple RNAi agents and routes of delivery
>> Use less siRNA
>> Reduces off target effects
>> Gentle and non-toxic

 

The T3 procedure does not require prior modification of the antibody or the RNAi agent and can be performed in a few simple steps. Click here for more information on T3™ Conjugation Kits.

 

The T3 Max kit replaces the original T3 kits as this single kit can now be used with any antibody.

 



RNAi Delivery System: MaxSuppressorâ„¢ In Vivo RNA-LANCEr II

MaxSuppressor™ In Vivo RNA-LANCEr II is a proprietary formulation composed of neutral lipid, non-ionic detergent, oil and small molecules which enable highly efficient delivery of RNAi agents into animals. This novel product has been shown to be more robust and efficient at penetrating tissues and organs than other delivery agents.

 

The procedure to package RNAi agents into the phospholipid-oil emulsion takes less than 1-hour. To use MaxSuppressor™ In Vivo RNA-LANCEr II simply mix 100 ug of your RNAi agent with a single tube of semi-dry MaxSuppressor™ In Vivo RNA-LANCEr II agent in total volume of less than 300 uL, in 1X PBS; extrude using the Lipid Extruder (Cat no 341007) with the supplied 100 nm pore sizing filters (or sonicate) and then directly inject into the animal.

 

For more information and pricing click here.

 


Relative GAPDH protein levels in the organs of rats injected with MaxSuppressor™ In Vivo RNA-LANCEr II containing GAPDH siRNA.  The relative levels of GAPDH are compared to rats treated with a negative control siRNA. 

 

MaxSuppressor™ In Vivo RNA-LANCEr II Graph

 

 



M-MuLV Reverse Transcriptase RNase H-

The M-MLV RT RNase H- is a genetically modified M-MLV Reverse Transcriptase, which lacks the ribonuclease H activity of normal M-MLV.

 

It synthesises a complementary DNA strand initiating from a primer using RNA (or single stranded DNA) as a template.

 

Most importantly removal of the RNase H activity results in an increase of full-length cDNA products.

 

Click here for more information and pricing