Newmarket Scientific Product Search Results for estrogen receptor

Product Search Results: estrogen receptor
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Product Search Results: estrogen receptor	Num Products Matched: 53	53	Prev 1 2 3 Next →

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Nordic BioSite

KSJ-XCUML3-96

96tests

£1021.00

Monosan

MON10208

1 ml

£1264.00

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Product Detail:	Rabbit anti-ESTROGEN RECEPTOR, clone ZR2 (Monoclonal)
Antibody Type:	Monoclonal
Host Animal:	Rabbit
Species Reactivity:	Human
Immunogen:	A synthetic peptide corresponding to residues on the C-terminus of human ER-?
Applications:	IHC-P (1:300)
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	Recognizes a protein of 67kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to antiestrogen (e.g. tamoxifen) therapy. Pretreatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH6.0, or in 50 mM Tris buffer pH9.5, for 20 minutes is required for IHC staining on formalin-fixed, paraffin embedded tissue sections. Note: Dilution of the antibody in 10% normal goat serum followed by a goat anti-rabbit secondary antibody-based detection is recommended. Control tissue Breast carcinoma. Staining nuclear.
Antibody Isotype:	IgG
Monosan Range:	MONOSAN
Clone:	ZR2
Concentration:	n/a
Format:	Concentrate
Storage buffer:	Tissue culture supernatant with 0.2% BSA and 15mM sodium azide
Storage:	2-8°C

Monosan

MON10203

1 ml

£1339.00

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Product Detail:	Rabbit anti-PROGESTERON RECEPTOR, clone ZR4 (Monoclonal)
Antibody Type:	Monoclonal
Host Animal:	Rabbit
Species Reactivity:	Human
Immunogen:	Recombinant protein encoding human progesterone receptor 412-526 aa
Applications:	IHC-P (1:200-1:400)
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	The progesterone receptor (PgR) is an estrogen regulated protein. It has been proposed that expression of PgR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies. Pretreatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH6.0 for 20 minutes is required for IHC staining on formalin-fixed, paraffin embedded tissue sections. Note: Dilution of the antibody in 10% normal goat serum followed by a goat anti-rabbit secondary antibody-based detection is recommended. Control tisse Breast, breast ducatl carcinoma. Staining Nuclear
Antibody Isotype:	IgG
Monosan Range:	MONOSAN
Clone:	ZR4
Concentration:	n/a
Format:	Concentrate
Storage buffer:	Tissue culture supernatant with 0.2% BSA and 15mM sodium azide
Storage:	2-8°C

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