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Product Search Results: R-053-100
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Product Search Results: R-053-100

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Biosensis R-053-100 100 µL £288.00
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Product Detail: Rabbit anti-Capsaicin receptor (TrpV1) Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
Background Info: TISSUE SPECIFICITY: Predominantly expressed in trigeminal and dorsal root sensory ganglia. Isoform 1 and isoform 3 are also expressed in brain and peripheral blood mononuclear cells.
Product Type: Antibody
Antibody Type: Polyclonal
Format: Lyophilized
Host Animal: Rabbit
Species Reactivity: Human,Mouse (Predicted),Rat
Immunogen: A synthetic peptide (YFSHLKEYVAS) of human capsaicin receptor protein (aa: 531-541) conjugated to KLH has been used as the immunogen.
Applications: IHC-Frozen
Antibody Isotype: Mixed
Application Details: IHC. Use at 1:1000 to 1:2000 dilution. This antibody has not been tested in other applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Alternative Names: Transient receptor potential cation channel subfamily V member 1; TrpV1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1; TRPV1; VR1; VR-1;
Biosensis Brand: Biosensis®
Conjugate: Unconjugated
Shelf Life: 12 months after date of receipt (unopened vial).
Use: For research use only.
Product references: Rehman R et al (2013) TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury. Int Immunopharmacol. 2013 Mar;15(3):597-605.
Specificity: Immunohistochemical analysis of rat DRG indicates a superb degree of specificity for this serum. This antibody is known to react with rat Capsaicin and due to sequence homology is expected to react with mouse Capsaicin . Other species have not yet been tested.
Storage: After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent.
Purification: Whole serum
Target: Capsaicin receptor (TrpV1)
Uniprot Number: Q8NER1