News and features


Antibodies, kits and reagents for immunohistochemistry (IHC) and cell biology

The Monosan range provides antibodies and kits for Immunohistochemistry (IHC).


MONOSAN antibodies are developed both by MONOSAN laboratories in house and in collaboration with universities and research institutes throughout Europe, ensuring that all MONOSAN antibodies are extensively tested.


Please use the search above to find antibodies to your specific marker protein using either the catalogue number or antigen name or simply use our contact form to ask us to search for you or request more information.


Antibodies to Breast Cancer Drug Resistance Proteins


Tumour cell insensitivity to anticancer drugs frequently appears as multidrug resistance (MDR), associated with the overexpression of one or more of a set of at least 10 different molecules, causing reduced drug levels at the intracellular target sites. These overexpressed molecules include transmembrane transporter proteins such as P glycoprotein, MRP1-9 and BCRP.


In addition, the lung-resistance protein, recently identified as the major vault protein, has been associated with MDR.

Our Monosan monoclonal antibodies specifically recognise these proteins and so can be used to help identify their roles in clinical drug resistance, and also explore their occurrence in normal human tissues and physiology. 


Clone MRPm5 reacts with an internal epitope of MRP1 (ABCC1), a 180-195 kD transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm5 was raised against a bacterial fusion protein of MRP1, containing amino acids 986-1204 of the protein. MRPm5 does not crossreact with the human MDR1 and MDR3 gene products.


Clone BXP-53 was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the Mouse BCRP (ABCG2) protein corresponding to amino acids 221-394, however BXP-53 also reacts with the Human BCRP molecule. BXP-53 reacts with an internal epitope of BCRP, a 70 kD transmembrane half-transporter which is involved in Multidrug resistance.


Follow the links below for further details and datsheets.


 anti MDR1 P-glycoprotein       anti MRP6 (ABCC6) 
 anti MDR3 P-glycoprotein      anti MRP7 (ABCC10)
 anti MRP1 (ABCC1)      anti MRP8 (ABCC11)  
 anti MRP2 (ABCC2)      anti MRP9 (ABCC12)
 anti MRP3 (ABCC3)      anti BCRP (ABCG2)
 anti MRP4 (ABCC4)      anti MVP / LRP
 anti MRP5 (ABCC5)      anti VPARP


Or if you have any questions simply use our contact form and we'll be happy to help.


Breast Cancer Marker Antibodies for Immunohistochemistry

There are a number of long established markers for breast cancer that are generally included in a standard breast cancer IHC panel. These are HER2, Estrogen Receptor (ER), Progestrogen Receptor (PR), Ki-67 and p53.


The Monosan range is able to provide antibodies to all 5 of these antibodies plus antibodies to other commonly used markers.


HER2 Antibodies

Estrogen Receptor (ER) Antibodies

Progesterone Receptor (PR) Antibodies

Ki-67 Antibodies

p53 Antibodies


Follow the links above to view the antibodies in each area or alternatively use the search above to find the specific product you are looking for. Or if you are having difficulty locating an antibody to a specific cancer marker, simply use our contact form and we'll look for you.


IHC Optimised Antibodies: CD14
AMACR P53 Androgen Receptor


We are happy to announce the availability of 4 new monosan antibodies for AMACR, P53, Androgen Receptor and CD14.


All 4 antibodies have been optimised and fine-tuned with regard to pretreatment methods, dilutions, incubation times, blocking and detection conditions in order to provide perfect immunohistochemistry results.


Available sizes are 0.1 ml, 1 ml and a ready-to-use 7ml vial. Pricing and further information is available on the individual links above.


Monosan optimised and fine

Anti-Adenovirus Antibody - Clone 20/11 & 2/6

This antibody is available in both concentrated and prediluted formats and is compatible with most automated platforms.


Adenoviruses are a group of viruses that can infect the membranes (tissue linings) of the respiratory tract, eyes, intestines, and urinary tract.  Localization of adenovirus occurs in the superficial epithelium/mucosa and adenovirus must be differentiated from CMV and HSV, which have similar overlapping morphological features (although CMV is localized in the endothelium).  Bone marrow, heart and lung transplant patients have a 5-10% chance of adenovirus infection.  Adenoviruses also account for about 10% of acute respiratory infections in children.


Anti adenovirus antibody
Cat No: MON3389 Cat No: MON-RTU1283
Name: Adenovirus (20/11 & 2/6) Name: Adenovirus (20/11 & 2/6)
Host: Mouse Host: Mouse
Isotype: IgG1/k Isotype: IgG1/k
Size: 1.0 ml concentrate Size: 7.0 ml predilute
Visualization: Cytoplasmic, Nuclear Visualization: Cytoplasmic, Nuclear
Dilution Range: 1:25-1:100 Dilution Range: prediluted
Click here for pricing Click here for pricing
Click here for a copy of the datasheet Click here for a copy of the datasheet