Newmarket Scientific Product Search Results for MDR1

Product Search Results: MDR1
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Nordic BioSite

AFC-LUIU8M-0.1

0.1 mg

£264.00

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Product Detail:	CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues, including the brain, liver, pancreas, testes, kidney, and blood (B, T, NK cells, but not monocytes).
Product Type:	Antibodies Primary
Antibody Type:	monoclonal
Storage Temp:	Store at 2-8°C. Do not freeze.
Immunogen:	NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
Applications:	FC,IP,IHC
Additional Info:	The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody preferentially recognizes CD243 in the process of transporting substrate.
Clone number:	UIC2
Antibody Isotype:	IgG2a k
Application Details:	Immunohistochemistry (paraffin sections): Heat mediated antigen retrieval in citrate buffer pH 6. Flow cytometry: Recommended dilution: 1-4 µg/ml
Biosite Brand:	BioSite Flow
Conjugation:	Unconjugated
Concentration:	1 mg/ml
Species Reactivity:	human
EntrezGene ID:	5243
UniProt No:	P08183

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Product Search Results: MDR1

Product Search Results: MDR1

Anti-Hu CD243 Purified