Newmarket Scientific Product Search Results for MDR1

Product Search Results: MDR1
Num Products Matched:	Prev 1 2 Next →
Product Search Results: MDR1	Num Products Matched: 26	26	Prev 1 2 Next →

Nordic BioSite

AFC-GFDXVY-100

100 tests

£454.00

Please sign in or sign up to order this product online.

Product Detail:	CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues, including the brain, liver, pancreas, testes, kidney, and blood (B, T, NK cells, but not monocytes).
Product Type:	Antibodies Primary
Antibody Type:	monoclonal
Storage Temp:	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Immunogen:	NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
Applications:	FC
Additional Info:	The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody preferentially recognizes CD243 in the process of transporting substrate.
Clone number:	UIC2
Antibody Isotype:	IgG2a k
Application Details:	Flow cytometry: The reagent is designed for analysis of human blood cells using 10 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Biosite Brand:	BioSite Flow
Conjugation:	APC
Species Reactivity:	human
EntrezGene ID:	5243
UniProt No:	P08183

Copyright Newmarket Scientific Ltd 2012. All trademarks are the property of their respective owners and are acknowledged where possible.	About Newmarket Scientific \| Terms and Conditions \| Cookie Policy Powered by SoftApps
About Newmarket Scientific Terms and Conditions Cookie Policy Powered by SoftApps

Cookies:

X We use cookies to help personalise and improve your web experience. By using our website you consent to our use of cookies, some of which may have already been set on your device. View our Cookie Policy to learn more.

Product Search Results: MDR1

Product Search Results: MDR1

Anti-Hu CD243 APC