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Product Search Results: AB18-10061 (100ug)

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Product Search Results: AB18-10061 (100ug)

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Newmarket Scientific - NS Reagents AB18-10061-100ug 100 µg £275.00
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Product Detail: Anti-RAMP2 Antibody (Polyclonal)
Background Info: Receptor Activity Modifying Protein 2 (RAMP2) is a member of the RAMP family of single-transmembrane-domain proteins, which are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.

RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor.

The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
Product Type: NS Reagents Antibody
Antibody Type: Polyclonal
Format: 100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp: 6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal: Rabbit
Species Reactivity: Human, Mouse, Rat
Expected Species: If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen: Partial length recombinant human RAMP2 from the N-terminal region
Applications: WB
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype: IgG
Application Details: WB 1:500-2000.
Antibody Number: 10061
Category: Primary Antibodies
Other names: RAMP2, Receptor Activity Modifying Protein 2, Calcitonin Receptor-Like Receptor Activity Modifying Protein 2
Research Areas: Cell Signalling and Transport, calcitonin-receptor-like receptor
NS Reagents Product Area: Cell Signalling
Molecular Weight: 20kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location: Membrane, Single-pass type I membrane protein
Purification: Affinity purification
Uniprot ID: O60895
Gene ID: 10266
Gene symbol: RAMP2
Release Date: Nov-18