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Newmarket Scientific








Product Search Results: Mouse anti-AMACR

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Product Search Results: Mouse anti-AMACR

Num Products Matched: 1 1

Product - please click for more details Brand Cat No Size Price (£)

Monosan MON5166-1 1 ml £775.00
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Product Detail: Mouse anti AMACR, clone BS2 (Monoclonal)
Antibody Type: Monoclonal
Host Animal: Mouse
Species Reactivity: human
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Applications: IHC-P (1:100-1:400)
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.
Antibody Isotype: IgG2b
Monosan Range: MONOSAN
Clone: BS2
Concentration: n/a
Format: Concentrate
Storage buffer: Tris Buffer, pH 7.2 with 0.03% Sodium Azide
Storage: 2-8°C