Newmarket Scientific Product Search Results for AX17-10018

Product Search Results: AX17-10018
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Product Search Results: AX17-10018	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AX17-10018-100ug

100 µg

£275.00

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Product Detail:	Anti-nMyc (Clone NMYC-1)
Background Info:	The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. N-Myc is highly expressed in pre B cell and the fetal brain and is critical for normal brain development. Overexpression of N-Myc is associated with a variety of tumors, most notably neuroblastomas and small lung carcinoma. This antibody does not react with c-Myc or L-Myc.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Mouse
Expected Species:	Mouse, Rat, Gibbon, Monkey, Hamster, Porcine, Chicken If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	A synthetic peptide from the C-terminal region of Human N-Myc
Applications:	ChIP ¦ IHC ¦ IF ¦ IP ¦ WB ¦ EMSA ¦ FC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone NMYC-1
Antibody Isotype:	IgG2b
Category:	Primary Antibodies
Other names:	N-myc proto-oncogene protein, basic helix-loop-helix protein 37 (bHLHe37), n-Myc, N-MYC
Research Areas:	DNA & Protein Modification, Cancer
NS Reagents Product Area:	DNA & Protein Modification
Peptide Sequence (Internal Use only):	Human N myc peptide sequence (SPYVESEDAPPQKC) conjugated to KLH (aa336-348) Full length protein is 464 aa in length 10 20 30 40 50 MPSCSTSTMP GMICKNPDLE FDSLQPCFYP DEDDFYFGGP DSTPPGEDIW 60 70 80 90 100 KKFELLPTPP LSPSRGFAEH SSEPPSWVTE MLLENELWGS PAEEDAFGLG 110 120 130 140 150 GLGGLTPNPV ILQDCMWSGF SAREKLERAV SEKLQHGRGP PTAGSTAQSP 160 170 180 190 200 GAGAASPAGR GHGGAAGAGR AGAALPAELA HPAAECVDPA VVFPFPVNKR 210 220 230 240 250 EPAPVPAAPA SAPAAGPAVA SGAGIAAPAG APGVAPPRPG GRQTSGGDHK 260 270 280 290 300 ALSTSGEDTL SDSDDEDDEE EDEEEEIDVV TVEKRRSSSN TKAVTTFTIT 310 320 330 340 350 VRPKNAALGP GRAQSSELIL KRCLPIHQQH NYAAPSPYVE SEDAPPQKKI 360 370 380 390 400 KSEASPRPLK SVIPPKAKSL SPRNSDSEDS ERRRNHNILE RQRRNDLRSS 410 420 430 440 450 FLTLRDHVPE LVKNEKAAKV VILKKATEYV HSLQAEEHQL LLEKEKLQAR 460 QQQLLKKIEH ARTC
Molecular Weight:	50kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Nucleus
Purification:	Protein A Affinity Purified
References:	Tasseva et al. 2011. J Biol Chem. 286(2):1061-73. PMID: 21068393.
Uniprot ID:	P04198
Gene ID:	4613
Gene symbol:	MYCN
Release Date:	October 2017

Newmarket Scientific - NS Reagents

AX17-10018-50ug

50 µg

£220.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-nMyc (Clone NMYC-1)
Background Info:	The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. N-Myc is highly expressed in pre B cell and the fetal brain and is critical for normal brain development. Overexpression of N-Myc is associated with a variety of tumors, most notably neuroblastomas and small lung carcinoma. This antibody does not react with c-Myc or L-Myc.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	50 µg in 50 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Mouse
Expected Species:	Mouse, Rat, Gibbon, Monkey, Hamster, Porcine, Chicken If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	A synthetic peptide from the C-terminal region of Human N-Myc
Applications:	ChIP ¦ IHC ¦ IF ¦ IP ¦ WB ¦ EMSA ¦ FC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone NMYC-1
Antibody Isotype:	IgG2b
Category:	Primary Antibodies
Other names:	N-myc proto-oncogene protein, basic helix-loop-helix protein 37 (bHLHe37), n-Myc, N-MYC
Research Areas:	DNA & Protein Modification, Cancer
NS Reagents Product Area:	DNA & Protein Modification
Peptide Sequence (Internal Use only):	Human N myc peptide sequence (SPYVESEDAPPQKC) conjugated to KLH (aa336-348) Full length protein is 464 aa in length 10 20 30 40 50 MPSCSTSTMP GMICKNPDLE FDSLQPCFYP DEDDFYFGGP DSTPPGEDIW 60 70 80 90 100 KKFELLPTPP LSPSRGFAEH SSEPPSWVTE MLLENELWGS PAEEDAFGLG 110 120 130 140 150 GLGGLTPNPV ILQDCMWSGF SAREKLERAV SEKLQHGRGP PTAGSTAQSP 160 170 180 190 200 GAGAASPAGR GHGGAAGAGR AGAALPAELA HPAAECVDPA VVFPFPVNKR 210 220 230 240 250 EPAPVPAAPA SAPAAGPAVA SGAGIAAPAG APGVAPPRPG GRQTSGGDHK 260 270 280 290 300 ALSTSGEDTL SDSDDEDDEE EDEEEEIDVV TVEKRRSSSN TKAVTTFTIT 310 320 330 340 350 VRPKNAALGP GRAQSSELIL KRCLPIHQQH NYAAPSPYVE SEDAPPQKKI 360 370 380 390 400 KSEASPRPLK SVIPPKAKSL SPRNSDSEDS ERRRNHNILE RQRRNDLRSS 410 420 430 440 450 FLTLRDHVPE LVKNEKAAKV VILKKATEYV HSLQAEEHQL LLEKEKLQAR 460 QQQLLKKIEH ARTC
Molecular Weight:	50kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Nucleus
Purification:	Protein A Affinity Purified
References:	Tasseva et al. 2011. J Biol Chem. 286(2):1061-73. PMID: 21068393.
Uniprot ID:	P04198
Gene ID:	4613
Gene symbol:	MYCN
Release Date:	October 2017

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Product Search Results: AX17-10018

Product Search Results: AX17-10018

Anti-N-Myc Antibody

Anti-N-Myc Antibody