Product Search Results : AX17-10012

Num PRODUCTS MATCHED : 2

Newmarket Scientific - NS Reagents

AX17-10012-50ug

50ug

£220.00

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Product Detail:	Anti-NSE (Clone NSEP2)
Background Info:	Neuron-specific enolase (NSE) is a glycolytic isoenzyme found in central and peripheral neurons and neuroendocrine cells. Enolase exists as a number of tissue-specific isoenzymes, consisting of homo or heterodimers of 3 different monomer-isoforms (alpha, beta, and gamma). Neuron specific enolase (NSE) is a 78 kD gamma-homodimer and represents the dominant enolase-isoenzyme found in neuronal and neuroendocrine tissues. NSE levels in other tissues, except erythrocytes, are negligible. Concentrations of NSE in serum or cerebrospinal fluid (CSF) are generally elevated in diseases which result in neuronal destruction. This antibody (Clone NSEP2) is not reactive with other isozyme forms of enolase.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Chicken, Mouse
Immunogen:	Ovalbumin-conjugated synthetic peptide corresponding to human NSE aa sequence:NSE-P2: aa 271-285 (TGDQLGALYQDFVRD)
Applications:	ELISA ¦ IHC ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	Gamma-enolase, enolase 2, ENO2, gamma-isozyme
Clone number:	Clone NSEP2
Antibody Isotype:	IgG1 kappa
Application Details:	WB: 1:2000 ELISA: 1:500
Antibody Number:	10012
Category:	Primary Antibodies
Research Areas:	Neuroscience
NS Product Area:	Neuroscience
Molecular Weight:	10012
References:	Murray GI, Duncan ME, Melvin WT, Fothergill JE. Immunohistochemistry of neurone specific enolase with gamma subunit specific anti-peptide monoclonal antibodies. J. Clin. Pathol. 46:993-996, 1993. Duncan ME, McAleese SM, Booth NA, Melvin WT, Fothergill JE. A simple enzyme-linked immunosorbent assay (ELISA) for the neuron-specific gamma isozyme of human enolase (NSE) using monoclonal antibodies raised against synthetic peptides corresponding to isozyme sequence differences. J. Immuno. Methods 151:227-236, 1992.
Release Date:	October 2017

Newmarket Scientific - NS Reagents

AX17-10012-100ug

100ug

£275.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-NSE (Clone NSEP2)
Background Info:	Neuron-specific enolase (NSE) is a glycolytic isoenzyme found in central and peripheral neurons and neuroendocrine cells. Enolase exists as a number of tissue-specific isoenzymes, consisting of homo or heterodimers of 3 different monomer-isoforms (alpha, beta, and gamma). Neuron specific enolase (NSE) is a 78 kD gamma-homodimer and represents the dominant enolase-isoenzyme found in neuronal and neuroendocrine tissues. NSE levels in other tissues, except erythrocytes, are negligible. Concentrations of NSE in serum or cerebrospinal fluid (CSF) are generally elevated in diseases which result in neuronal destruction. This antibody (Clone NSEP2) is not reactive with other isozyme forms of enolase.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Chicken, Mouse
Immunogen:	Ovalbumin-conjugated synthetic peptide corresponding to human NSE aa sequence:NSE-P2: aa 271-285 (TGDQLGALYQDFVRD)
Applications:	ELISA ¦ IHC ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	Gamma-enolase, enolase 2, ENO2, gamma-isozyme
Clone number:	Clone NSEP2
Antibody Isotype:	IgG1 kappa
Application Details:	WB: 1:2000 ELISA: 1:500
Antibody Number:	10012
Category:	Primary Antibodies
Research Areas:	Neuroscience
NS Product Area:	Neuroscience
Molecular Weight:	10012
References:	Murray GI, Duncan ME, Melvin WT, Fothergill JE. Immunohistochemistry of neurone specific enolase with gamma subunit specific anti-peptide monoclonal antibodies. J. Clin. Pathol. 46:993-996, 1993. Duncan ME, McAleese SM, Booth NA, Melvin WT, Fothergill JE. A simple enzyme-linked immunosorbent assay (ELISA) for the neuron-specific gamma isozyme of human enolase (NSE) using monoclonal antibodies raised against synthetic peptides corresponding to isozyme sequence differences. J. Immuno. Methods 151:227-236, 1992.
Release Date:	October 2017

Product Search Results : AX17-10012

Anti-NSE Antibody

Anti-NSE Antibody