Product Search Results : AB18-10063

Num PRODUCTS MATCHED : 2

Newmarket Scientific - NS Reagents

AB18-10063-50ug

50ug

£220.00

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Product Detail:	Anti-CPT1A Polyclonal Antibody
Background Info:	Carnitine palmitoyltransferase I (CPT1) is a liver enzyme involved in fatty acid oxidation. Three isoforms of CPT1 are currently known: CPT1A, CPT1B, and CPT1C. This antibody recognises CPT1A. The carnitine palmitoyltransferase (CPT) enzyme system, with acyl-CoA synthetase and carnitine/acylcarnitine translocas, provide the mechanism for long-chain fatty acids to be transferred from the cytosol to the mitochondrial matrix to undergo beta-oxidation for energy production. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. Carnitine palmitoyltransferase I is responsible for the formation of acyl carnitines, catalysing the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine, allowing movement of the acyl carnitine from the cytosol into the intermembrane space of mitochondria. CPT I is key for carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	50 µg in 50 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human Mouse
Immunogen:	Recombinant human CPT1A
Applications:	WB IF IP
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	CPT1, CPT1-L, L-CPT1, Carnitine palmitoyltransferase IA
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IF 1:50-200. IP 1:50-100.
Antibody Number:	10063
Category:	Primary Antibodies
Research Areas:	Cell Signalling and Transport, Transcription and Translation, Protein Modification, Transcription, Chromatin
NS Product Area:	Cell Signalling and Transport
Molecular Weight:	88kDa
Subcellular location:	Mitochondrion outer membrane, Multi-pass membrane protein
Purification:	Affinity purification
Uniprot ID:	P50416
Gene ID:	1374
Release Date:	November 2018

Newmarket Scientific - NS Reagents

AB18-10063-100ug

100ug

£275.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-CPT1A Polyclonal Antibody
Background Info:	Carnitine palmitoyltransferase I (CPT1) is a liver enzyme involved in fatty acid oxidation. Three isoforms of CPT1 are currently known: CPT1A, CPT1B, and CPT1C. This antibody recognises CPT1A. The carnitine palmitoyltransferase (CPT) enzyme system, with acyl-CoA synthetase and carnitine/acylcarnitine translocas, provide the mechanism for long-chain fatty acids to be transferred from the cytosol to the mitochondrial matrix to undergo beta-oxidation for energy production. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. Carnitine palmitoyltransferase I is responsible for the formation of acyl carnitines, catalysing the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine, allowing movement of the acyl carnitine from the cytosol into the intermembrane space of mitochondria. CPT I is key for carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human Mouse
Immunogen:	Recombinant human CPT1A
Applications:	WB IF IP
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	CPT1, CPT1-L, L-CPT1, Carnitine palmitoyltransferase IA
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IF 1:50-200. IP 1:50-100.
Antibody Number:	10063
Category:	Primary Antibodies
Research Areas:	Cell Signalling and Transport, Transcription and Translation, Protein Modification, Transcription, Chromatin
NS Product Area:	Cell Signalling and Transport
Molecular Weight:	88kDa
Subcellular location:	Mitochondrion outer membrane, Multi-pass membrane protein
Purification:	Affinity purification
Uniprot ID:	P50416
Gene ID:	1374
Release Date:	November 2018

Product Search Results : AB18-10063

Anti-CPT1A Antibody

Anti-CPT1A Antibody