Product Search Results : AB18-10059

Num PRODUCTS MATCHED : 2

Newmarket Scientific - NS Reagents

AB18-10059-50ug

50ug

£220.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-PRMT6 Polyclonal Antibody
Background Info:	Protein arginine N-methyltransferase 6 (PRMT6) like other arginine N-methyltransferases, catalyses the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. PRMT6 catalyses both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of histone H3 arginine 2 (H3R2me2a) and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	50 µg in 50 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human Mouse Rat
Immunogen:	Recombinant human PRMT6
Applications:	WB IF
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	HRMT1L6, PROTEIN ARGININE N-METHYLTRANSFERASE 6, Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 6 , HMT1 HnRNP Methyltransferase-Like 6, HMT1 HnRNP
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IF 1:50-200.
Antibody Number:	10059
Category:	Primary Antibodies
Research Areas:	Transcription and Translation, Protein Modification, Transcription, Chromatin
NS Product Area:	Protein and Nucleic Acid Modification
Molecular Weight:	42kDa
Subcellular location:	Nucleus
Purification:	Affinity purification
Uniprot ID:	Q96LA8
Gene ID:	55170
Release Date:	October 2018

Newmarket Scientific - NS Reagents

AB18-10059-100ug

100ug

£275.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-PRMT6 Polyclonal Antibody
Background Info:	Protein arginine N-methyltransferase 6 (PRMT6) like other arginine N-methyltransferases, catalyses the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. PRMT6 catalyses both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of histone H3 arginine 2 (H3R2me2a) and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human Mouse Rat
Immunogen:	Recombinant human PRMT6
Applications:	WB IF
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Alternative Name:	HRMT1L6, PROTEIN ARGININE N-METHYLTRANSFERASE 6, Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 6 , HMT1 HnRNP Methyltransferase-Like 6, HMT1 HnRNP
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IF 1:50-200.
Antibody Number:	10059
Category:	Primary Antibodies
Research Areas:	Transcription and Translation, Protein Modification, Transcription, Chromatin
NS Product Area:	Protein and Nucleic Acid Modification
Molecular Weight:	42kDa
Subcellular location:	Nucleus
Purification:	Affinity purification
Uniprot ID:	Q96LA8
Gene ID:	55170
Release Date:	October 2018

Product Search Results : AB18-10059

Anti-PRMT6 Antibody

Anti-PRMT6 Antibody