Newmarket Scientific
Newmarket Scientific

Product Search Results: AA17-10047

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Product Search Results: AA17-10047

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Newmarket Scientific - NS Reagents AA17-10047-50ul 50 µl £258.00
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Product Detail: Anti-BFAR Antibody
Background Info: Bifunctional apoptosis regulator (BFAR/BAR) is a multidomain protein originally identified as an inhibitor of Bax-induced apoptosis. It is predominantly found in the endoplasmic reticulum (ER) and is thought to be a scaffold protein that may bridge components of both extrinsic and intrinsic apoptosis pathways.

BFAR contains a DED (death effector domain) like domain that suppresses death receptor apoptosis signalling pathways. It is highly expressed in the brain and is believed to be involved in regulating neuronal survival, helping neurons to survive for the entire lifetime of the organism by playing a central role in inhibiting ER initiated apoptosis.
Product Type: NS Reagents Antibody
Antibody Type: Polyclonal
Format: Sera with Sodium Azide
Storage Temp: 6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal: Rabbit
Species Reactivity: Human
Immunogen: A synthetic peptide of BFAR (BAR) protein aa 3-21 (EPQKSYVNTMDLERDEPLK)
Applications: IP ¦ IHC ¦ WB
Alternative Name: Bifunctional apoptosis regulator, BFAR, BAR, RNF47
Antibody Isotype: IgG
Application Details: WB: 1:1000-1:2000
IHC (paraffin): 1:1000-1:5000
IHC (frozen): 1:1000-1:2000
IP: 1:50-1:200
Category: Primary Antibodies
Research Areas: Neuroscience
NS Reagents Product Area: Neuroscience
Uniprot ID: Q9NZS9
Gene ID: 51283
Release Date: Dec-17