| Product - please click for more details |
Brand |
Cat No |
Size |
Price (£) |
|
| CD74 Antibody: APC |
StressMarq |
SMC-268D-APC |
100 µg |
£309.00
|
|
| Product Detail: |
CD74 Antibody, Clone 3D7: APC |
| Background Info: |
CD74 is a non-polymorphic type II integral membrane protein. It has a short N-terminal cytoplasmic tail of 28 amino acids, followed by a single 24-aa transmembrane region and an approximately 150-aa lumenal domain (1). The CD74 chain is thought to function mainly as an MHC class II chaperone, which promotes ER exit of MHC class II molecules, directs them to endocytic compartments, prevents peptide binding in the ER, and contributes to peptide editing in the MHC class II compartment.
Class II MHC and Ii expression was believed to be restricted to classical antigen-presenting cells (APC); however, during inflammation, other cell types, including mucosal epithelial cells, have also been reported to express class II MHC molecules (2). Experiments that investigate cell-surface CD74 are complicated by the fact that CD74 remains on the cell surface for a very short time. The surface half-life of CD74 was calculated to be fewer than 10 minutes (3). CD74 however has also recently been shown to have a role as an accessory-signaling molecule because of its high-affinity binding to the pro-inflammatory cytokine, macrophage migration-inhibitory factor (MIF) (3). The restricted expression of CD74 by normal tissues and its very rapid internalization make CD74 an attractive therapeutic target for both cancer and immunologic diseases (4). |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu |
| Immunogen: |
Human CD74 invariant chain synthetic peptide. |
| Applications: |
WB | FCM | FACS |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
3D7 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); FACS (1:50); optimal dilutions for assays should be determined by the user. |
| Target: |
CD74 |
| Conjugate: |
APC |
| Research Area(s): |
Immunology | Adaptive Immunity | B Cells | B Cell CD Markers |
| Alternative Name(s): |
DHLAG Antibody, HLA DR gamma Antibody, HLADG Antibody, p33 Antibody, p35 Antibody, Protein 41 Antibody, CD 74 Antibody, CD74 Antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Antibody, CD74 antigen Antibody, CD74 molecule Antibody, CD74 molecule, major histocompatibility complex, class II invariant chain Antibody, CLIP Antibody, DHLAG Antibody, Gamma chain of class II antigens Antibody, HG2A_HUMAN Antibody, HLA class II histocompatibility antigen gamma chain Antibody, HLA DR antigens associated invariant chain Antibody, HLA DR gamma Antibody, HLA-DR antigens-associated invariant chain Antibody, HLA-DR-gamma Antibody, HLADG Antibody, HLADR antigens associated invariant chain Antibody
Ia antigen associated invariant chain Antibody, Ia antigen-associated invariant chain Antibody, Ia associated invariant chain Antibody, Ia gamma Antibody, Ii Antibody, Invariant polypeptide of major histocompatibility complex class II antigen associated Antibody, la-gamma Antibody, Major histocompatibility complex class II invariant chain Antibody, MHC HLA DR gamma chain Antibody, MHC HLA-DR gamma chain Antibody, p33 Antibody, p35 Antibody, Protein 41 Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001020329.1 |
| Gene ID: |
972 |
| Swiss-Prot: |
P04233 |
| Species Reactivity Full Name: |
Human |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~33 kDa protein. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
A 1:1000 dilution of SMC-268 was sufficient for detection of CD74 in 15 µg of B-Cell Lymphoma cell line Raji by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody. |
| Cellular Localization: |
Cell Membrane | Endoplasmic Reticulum | Endoplasmic Reticulum Membrane | Golgi Apparatus | Endosome | Lysosome |
| References: |
1. Becker-Hermann, S., Arie, G., Medvedovsky H, Kerem A, and Shachar I. (2005) Mol Bio Cell. 16(11):5061-9.
2. Barrera CA., et al (2005) J Histochem Cytochem 53 (12): 1481-9.
3. Starlets D., et al. (2006) Blood. 107 (12): 4807-4816.
4. Burton JD., et al. (2004). Clin Cancer Res. 10(19): 6606-11.
5. Denzin L.K., Hammond, C. and Cresswell, P. (1996) J. Exp. Med. 184: 2153-2165.
6. Denzin L.K., Robbins N.F., Carboy-Newcomb C. and Cresswell P. (1994) Immunity 1: 595-606. |
| Launch Date: |
23/Mar/2017 |
| Tarriff Code: |
3002.15.0000 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-268D-APC, RRID: AB_2699980 |
|
| GFAP Antibody |
StressMarq |
SMC-441D |
100 µg |
£268.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Unconjugated |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D, RRID: AB_2701685 |
|
| GFAP Antibody: ATTO 390 |
StressMarq |
SMC-441D-A390 |
100 µg |
£311.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 390 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 390 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A390, RRID: AB_2701686 |
|
| GFAP Antibody: ATTO 488 |
StressMarq |
SMC-441D-A488 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 488 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 488 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A488, RRID: AB_2701687 |
|
| GFAP Antibody: ATTO 565 |
StressMarq |
SMC-441D-A565 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 565 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 565 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A565, RRID: AB_2701688 |
|
| GFAP Antibody: ATTO 594 |
StressMarq |
SMC-441D-A594 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 594 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 594 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A594, RRID: AB_2701689 |
|
| GFAP Antibody: ATTO 633 |
StressMarq |
SMC-441D-A633 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 633 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 633 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A633, RRID: AB_2701690 |
|
| GFAP Antibody: ATTO 655 |
StressMarq |
SMC-441D-A655 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 655 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 655 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A655, RRID: AB_2701691 |
|
| GFAP Antibody: ATTO 680 |
StressMarq |
SMC-441D-A680 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 680 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 680 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A680, RRID: AB_2701692 |
|
| GFAP Antibody: ATTO 700 |
StressMarq |
SMC-441D-A700 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: ATTO 700 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 700 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-A700, RRID: AB_2701693 |
|
| GFAP Antibody: Alkaline Phosphatase |
StressMarq |
SMC-441D-ALP |
100 µg |
£305.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: Alkaline Phosphatase |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Alkaline Phosphatase |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-ALP, RRID: AB_2701694 |
|
| GFAP Antibody: APC |
StressMarq |
SMC-441D-APC |
100 µg |
£309.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: APC |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
APC |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-APC, RRID: AB_2701695 |
|
| GFAP Antibody: Biotin |
StressMarq |
SMC-441D-BI |
100 µg |
£307.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: Biotin |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Biotin |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-BI, RRID: AB_2701696 |
|
| GFAP Antibody: FITC |
StressMarq |
SMC-441D-FITC |
100 µg |
£303.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: FITC |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
FITC |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-FITC, RRID: AB_2701697 |
|
| GFAP Antibody: HRP |
StressMarq |
SMC-441D-HRP |
100 µg |
£299.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: HRP |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
HRP |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-HRP, RRID: AB_2701698 |
|
| GFAP Antibody: PE/ATTO 594 |
StressMarq |
SMC-441D-P594 |
100 µg |
£317.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: PE/ATTO 594 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
PE/ATTO 594 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-P594, RRID: AB_2701699 |
|
| GFAP Antibody: PerCP |
StressMarq |
SMC-441D-PCP |
100 µg |
£309.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: PerCP |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
PerCP |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-PCP, RRID: AB_2701700 |
|
| GFAP Antibody: RPE |
StressMarq |
SMC-441D-RPE |
100 µg |
£308.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: RPE |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
RPE |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-RPE, RRID: AB_2701701 |
|
| GFAP Antibody: Streptavidin |
StressMarq |
SMC-441D-STR |
100 µg |
£308.00
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8: Streptavidin |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Streptavidin |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441D-STR, RRID: AB_2701702 |
|
| GFAP Antibody |
StressMarq |
SMC-441S |
12 µg |
30
|
|
| Product Detail: |
GFAP Antibody, Clone S206A-8 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
|
| Applications: |
WB | IHC | ICC/IF |
| Clone number: |
S206A-8 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Unconjugated |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins. |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
24-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-441S, RRID: AB_2701685 |
|
| GFAP R416WT Antibody |
StressMarq |
SMC-442D |
100 µg |
£268.00
|
|
| Product Detail: |
GFAP R416WT Antibody, Clone S206B-9 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin).
|
| Applications: |
WB | IHC | ICC/IF |
| Clone number: |
S206B-9 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
Unconjugated |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results). |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-442 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
28-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-442D, RRID: AB_2701703 |
|
| GFAP R416WT Antibody: ATTO 390 |
StressMarq |
SMC-442D-A390 |
100 µg |
£311.00
|
|
| Product Detail: |
GFAP R416WT Antibody, Clone S206B-9: ATTO 390 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin).
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206B-9 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 390 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results). |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-442 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
28-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-442D-A390, RRID: AB_2701704 |
|
| GFAP R416WT Antibody: ATTO 488 |
StressMarq |
SMC-442D-A488 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP R416WT Antibody, Clone S206B-9: ATTO 488 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin).
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206B-9 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 488 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results). |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-442 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
28-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-442D-A488, RRID: AB_2701705 |
|
| GFAP R416WT Antibody: ATTO 565 |
StressMarq |
SMC-442D-A565 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP R416WT Antibody, Clone S206B-9: ATTO 565 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin).
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206B-9 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 565 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results). |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-442 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
28-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-442D-A565, RRID: AB_2701706 |
|
| GFAP R416WT Antibody: ATTO 594 |
StressMarq |
SMC-442D-A594 |
100 µg |
£310.00
|
|
| Product Detail: |
GFAP R416WT Antibody, Clone S206B-9: ATTO 594 |
| Background Info: |
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Product Type: |
Antibodies |
| Format: |
PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Storage Temp: |
-20ºC |
| Host Animal: |
Mouse |
| Species Reactivity: |
Hu | Ms | Rt |
| Immunogen: |
Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin).
|
| Applications: |
WB | IHC | ICC/IF |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Clone number: |
S206B-9 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Target: |
GFAP |
| Conjugate: |
ATTO 594 |
| Research Area(s): |
Neuroscience | Cell Markers | Glial Markers | Astrocyte Markers |
| Alternative Name(s): |
Glial fibrillary acidic protein Antibody, Intermediate filament protein Antibody, Astrocyte Antibody, gfapl Antibody, DKFZp459C0729 Antibody, MGC139638 Antibody, FLJ45472 Antibody, AI836096 Antibody, GFAP Antibody |
| Category: |
Monoclonal |
| Immunogen Species: |
Human |
| Accession Number: |
NP_001124491.1 |
| Gene ID: |
2670 |
| Swiss-Prot: |
P14136 |
| Species Reactivity Full Name: |
Human | Mouse | Rat |
| Purification: |
Protein G Purified |
| Concentration: |
1 mg/ml |
| Specificity: |
Detects ~50kDa. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results). |
| Shipping Temperature: |
Blue Ice or 4ºC |
| Certificate of Analysis: |
1 µg/ml of SMC-442 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization: |
Cytoplasm |
| References: |
1. Velasco M.E., et al. (1980) Cancer. 45:484.
2. Bonnin J.M., et al. (1984) Acta Neuropathology. 62:185.
3. Lee VM-Y., et al. (1984) J. Neurochem. 42:25-32 (1984).
4. Trojanowski JQ et al. (1986) J. Neurochem. 6(3): 650-660 (1986).
5. Schmidt ML et al; Lab Invest 56:282-294 (1987).
6. Kosik KS et al; Neuron 1:817-825 (1988).
7. Schmidt ML et al; Lab Invest 59:460-466 (1988).
8. Mokuna, K, et al: J Neurosci Res 23:396 (1989).
9. Molenaar, et al; Exp Neurology 108:1-9 (1990).
10. Tohyama T et al; Am J Pathol, 142:871-882 (1993).
11. Tohyama T et al; Am J Pathol 142:883-892 (1993).
12. Thilenius, A.R.B., et al; J. Immunol. 162(2): 643-650 (1999). |
| Launch Date: |
28-Oct-2013 |
| Tarriff Code: |
3002.10.0290 |
| ADR Code: |
Non-hazardous |
| UN Code for transport: |
Non-hazardous |
| Country of Origin: |
Canada |
| Cite this Product: |
StressMarq Biosciences Cat# SMC-442D-A594, RRID: AB_2701707 |
|
