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Product Search Results: 3420-01

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Product Search Results: 3420-01

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Product - please click for more details Brand Cat No Size Price (£)

Monosan MONX11062 1 ml £591.00
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Product Detail: Mouse anti-Interleukin 6, clone 10C12 (monoclonal)
Antibody Type: Monoclonal
Host Animal: Mouse
Species Reactivity: human
Immunogen: A prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule
Applications: IHC-P (1:50)
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: IL-6 is a multifunctional cytokine that is secreted by both lymphoid and non-lymphoid cells. It plays a key role in immune responses, hematopoiesis and is an important cytokine in cell proliferation and differentiation. It may also play an important role as an autocrine growth factor in metastatic prostate cancer. IL-6 has been reported to play a role in secretion or release of pituitary hormone in pituitary hormone secreting cells and adenomas. In addition, IL-6 has been suggested to have a trophic effect in nerve cells and to have a direct pathogenic role in CNS disorders. There are an increasing number of reports that cytokines of the IL-6 family play an important regulatory role in heart physiology.
Antibody Isotype: IgG2a
Monosan Range: MONXtra
Clone: 10C12
Concentration: n/a
Storage buffer: Tissue culture supernatant with 15mM Sodium azide
Storage: 2-8°C
References 1: Salgado R et al. International Journal of Cancer. 103 (5): 642–646 (2003)
References 2: Kurotani R et al. Modern Pathology. 14 (8): 791–797 (2001)
References 3: Menet E et al. European Cytokine Network. 12 (4): 639–646 (2001)
References 4: Ono S et al. Journal of the Neurological Sciences. 187 (1–2): 27–34 (2001)
References 5: Yasukawa K et al. The EMBO Journal. 6 (10): 2939–2945 (1987)