Newmarket Scientific Product Search Results for AX17-10013

Product Search Results: AX17-10013
Num Products Matched:
Product Search Results: AX17-10013	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AX17-10013-100ug

100 µg

275

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Product Detail:	Anti-ANO5 (Clone 5F7)
Background Info:	Anoctamin-5 (ANO5) is believed to be an integral membrane glycoprotein with a role in myogenesis and osteogenesis. It is found predominantly in the plasma membrane and intracellular membrane vesicles. In human tissues, ANO5 mRNA is detected in the brain, heart, kidney, lung and skeletal muscle, and in mice shows abundant expression in bone tissues including the calvarium, femur and mandible. Mutations in this protein are linked to limb-girdle muscular dystrophy type 2L (LGMD2L), Miyoshi muscular dystrophy 3 (MMD3) and Gnathodiaphyseal dysplasia (GDD) and other dysferlinopathies. ANO5 has an expected molecular mass of around 107kDa. However in western blot using lysates prepared from C2C12 cells (wt), RD and fibroblasts, 3 bands are detected at 107kDa, 55 kDa and 37 KDa.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Mouse, Rat
Expected Species:	Very likely to bind to Anoctamin from other species due to 100% homology in Sheep, Goat, Dog and Cat If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	A synthetic peptide from the C-terminal region of Human ANO5
Applications:	IF ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the productiion of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone 5F7
Antibody Isotype:	IgM
Antibody Number:	10013
Category:	Primary Antibodies
Other names:	Anoctamin-5, ANO5
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Molecular Weight:	37kDa, 55kDa and 107kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Cell membrane, Endoplasmic reticulum membrane
Purification:	Affinity Purified
References:	Bashir et al. 2014. Neuromuscular Disorders. 24:1
Uniprot ID:	Q75V66
Gene ID:	203859
Gene symbol:	ANO5
Release Date:	Oct-17

Newmarket Scientific - NS Reagents

AX17-10013-50ug

50 µg

220

Please sign in or sign up to order this product online.

Product Detail:	Anti-ANO5 (Clone 5F7)
Background Info:	Anoctamin-5 (ANO5) is believed to be an integral membrane glycoprotein with a role in myogenesis and osteogenesis. It is found predominantly in the plasma membrane and intracellular membrane vesicles. In human tissues, ANO5 mRNA is detected in the brain, heart, kidney, lung and skeletal muscle, and in mice shows abundant expression in bone tissues including the calvarium, femur and mandible. Mutations in this protein are linked to limb-girdle muscular dystrophy type 2L (LGMD2L), Miyoshi muscular dystrophy 3 (MMD3) and Gnathodiaphyseal dysplasia (GDD) and other dysferlinopathies. ANO5 has an expected molecular mass of around 107kDa. However in western blot using lysates prepared from C2C12 cells (wt), RD and fibroblasts, 3 bands are detected at 107kDa, 55 kDa and 37 KDa.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	50 µg in 50 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human, Mouse, Rat
Expected Species:	Very likely to bind to Anoctamin from other species due to 100% homology in Sheep, Goat, Dog and Cat If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	A synthetic peptide from the C-terminal region of Human ANO5
Applications:	IF ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the productiion of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone 5F7
Antibody Isotype:	IgM
Antibody Number:	10013
Category:	Primary Antibodies
Other names:	Anoctamin-5, ANO5
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Molecular Weight:	37kDa, 55kDa and 107kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Cell membrane, Endoplasmic reticulum membrane
Purification:	Affinity Purified
References:	Bashir et al. 2014. Neuromuscular Disorders. 24:1
Uniprot ID:	Q75V66
Gene ID:	203859
Gene symbol:	ANO5
Release Date:	Oct-17

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Product Search Results: AX17-10013

Product Search Results: AX17-10013

Anti-Anoctamin-5 Antibody

Anti-Anoctamin-5 Antibody