| Product Detail: |
Vasopressin Antibody |
| Background Info: |
Raised to arginine vasopressin coupled to bovine thyroglobulin with carbodiimide . |
| Product Type: |
Antibody - Antibodies |
| Antibody Type: |
polyclonal |
| Format: |
Lyophilised |
| Host Animal: |
Rabbit |
| Species Reactivity: |
Anole, Bluehead Wrasses (Fish), Chicken, Clarias Batrachus (Catfish), Cockroach, Ewe / Sheep, Hamster, Human, Hydra Vulgaris (Polyp), Locust, Mole Rat, Monkey, Mouse, Pigeon, Rat, Sheep, Shrew, Squirrel |
| Immunogen: |
Arg Vasopressin |
| Applications: |
Immunohistochemistry, Immunocytochemistry, immunofluorescence |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Additional Info: |
The antibody has a proven strong fluorescent staining at a 1/400 - 1/800 dilution and a proven strong biotin-streptavidin/HRP staining at a 1/2000 - 1/4000 dilution in rat hypothalamus. Staining is completely eliminated by pretreatment of the diluted antibody with 10 µg/mL of arginine vasopressin. Pre-adsorption with as much as 100 µg/mL of oxytocin had no effect on immunolabeling. |
| Gene Symbol: |
AVPR2 |
| NCBI Gene Aliases: |
ADHR,DI1,DIR,DIR3,MGC126533,MGC138386,NDI,V2 |
| PubMed IDs: |
1472991, 1430326, 1351936, 1332223, 1284440, 1282727, 21525287, 20506472, 12111539, 25051448 |
| Product category: |
Diabetes, Transcription Factor, Tumor Markers, Viral |
|
| Product Detail: |
ARHGEF4 (Rho guanine nucleotide exchange factor 4), also known as ASEF 1 (adenomatous polyposis coli – stimulated guanine nucleotide exchange factor 1) is an approximately 80 kDa cytoplasmic protein important for growth factor-mediated regulation of cell morphology and migration. Besides N-terminal adenomatous polyposis coli (APC)-binding region (ABR) it contains Dbl homology (DH), pleckstrin homology (PH) and SH3 domains. The SH3 domain inhibits GEF activity of ARHGEF4 by intramolecular interaction with the DH domain, whereas binding of APC stimulates the GEF activity. Activated ARHGEF4 stimulates the small GTPase Cdc42, which leads to decreased cell-cell adherence and enhanced cell migration. |
| Product Type: |
Antibodies Primary |
| Antibody Type: |
monoclonal |
| Storage Temp: |
Store at 2-8°C. Do not freeze. |
| Immunogen: |
Recombinant fragment of human ARHGEF4 (amino acids 143-271) |
| Applications: |
FC,WB |
| Additional Info: |
The mouse monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain. |
| Clone number: |
ARHGEF-08 |
| Antibody Isotype: |
IgG1 |
| Application Details: |
Flow cytometry: Recommended dilution: 1-4 ?g/ml. Intracellular staining. |
| Biosite Brand: |
BioSite Flow |
| Conjugation: |
Unconjugated |
| Concentration: |
1 mg/ml |
| Species Reactivity: |
human |
| EntrezGene ID: |
50649 |
| UniProt No: |
Q9NR80 |
|
