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Product Search Results: 1122-01

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Product Search Results: 1122-01

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Product - please click for more details Brand Cat No ▲ Size Price (£)

Monosan MON9844 100 ug £290.00
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Product Detail: Mouse anti-Vascular Endothelial Growth Factor (VEGF), clone VEGF-21 (Monoclonal)
Antibody Type: Monoclonal
Host Animal: Mouse
Species Reactivity: human, dog, mouse, rabbit, rat
Immunogen: human VEGF189 recombinant protein
Applications: FC, IHC-fr, IHC-P, IF
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: VEGF-21 reacts with Vascular Endothelial Growth Factor, also known as Vascular Permeability Factor (VEGF/ VPF) and is the key mediator of angiogenesis. The MWs are 19- 22kDa (reducing) and 38kDa-44kDa (non-reducing). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis. In addition to endothelial cells, VEGF and VEGF receptors are expressed on numerous non-endothelial cells including tumor cells.
Antibody Isotype: IgG1-K
Monosan Range: MONOSAN
Clone: VEGF-21
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Storage: 2-8°C
References 1: Tischer E. et al. J. Biol. Chem 266: 11947-11954 (1991)
References 2: Berse B. et al, Mol. Biol. Cell 3: 211-220 (1992)
References 3: Folkman J. et al, Nature 339: 58-61 (1989)