Newmarket Scientific Product Search Results for 5145

Product Search Results: 5145
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Nordic BioSite

AFC-W48URB-100

100 tests

£365.00

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Product Detail:	CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
Product Type:	Antibodies Primary
Antibody Type:	monoclonal
Storage Temp:	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Immunogen:	Human platelets
Applications:	FC
Additional Info:	The mouse monoclonal antibody AK2 recognizes an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent complex with CD42a and CD42d.
Clone number:	AK2
Antibody Isotype:	IgG1
Application Details:	Flow cytometry: The reagent is designed for analysis of human blood cells using 4 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Biosite Brand:	BioSite Flow
Conjugation:	FITC
Species Reactivity:	human
EntrezGene ID:	2811
UniProt No:	P07359

Nordic BioSite

AFC-Y6GBRE-100

100 tests

£454.00

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Product Detail:	CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
Product Type:	Antibodies Primary
Storage Temp:	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Immunogen:	Human platelets
Applications:	FC
Additional Info:	The mouse monoclonal antibody AK2 recognizes an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent complex with CD42a and CD42d.
Clone number:	AK2
Antibody Isotype:	IgG1
Application Details:	Flow cytometry: The reagent is designed for analysis of human blood cells using 10 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Biosite Brand:	BioSite Flow
Species Reactivity:	human
EntrezGene ID:	2811
UniProt No:	P07359

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