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Newmarket Scientific








News: Biosensis α-synuclein RapidTM ELISA Kit



Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system that has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD) leading to subsequent discoveries of further mutations in the alpha-synuclein gene in familial PD.

 

Aggregated proteinaceous inclusions called Lewy bodies which are found in Parkinson's disease and cortical Lewy body dementia (LBD) were shown to be predominantly alpha-synuclein and aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies.

 

Alpha-synuclein is therefore a key target in neurodegenerative disease research.

 

The Biosensis Alpha-Synuclein Rapid ELISA Kit (BEK-2216-1P/2P) lets you quantifiy human alpha-synuclein in human citrate-plasma, serum and CSF, in less than 4 hours.

 

Key features:

• Low intra-assay and inter-assay CVs of < 10%

• Fast (< 4 hours)

• Consistent assay performance

• Real validation data showing accurate quantification in human blood and CSF

 

Biosensis alpha-synuclein ELISA Kit

 

Related products:

Biosensis chicken alpha-synuclein antibody

Biosensis sheep anti alpha-synuclein antibodies

Biosensis rabbit anti alpha-synuclein antibody

Phospho-synuclein antibodies