Neuroscience


Proteins, antibodies, kits and other reagents for neuroscience


Affinity Biosciences logo   Agrisera logo     Biosensis logo   ImmunoStar logo  NS Reagents logo  StressMarq logo 

 


 

Newmarket Scientific provides products for neuroscience including:

 

Antibodies, Proteins, Immunohistochemistry kits and Related reagents.

 

Please visit our immunohistochemistry page for details of our IHC kits or if you are having difficulty locating an item, simply use our contact form and we'll look for you.

 

More information on neuroscience research including highlighted papers and other resources is available on our Exosome Twitter feed:

 



Biosensis MOAB-2 antibody to Amyloid beta peptide (40/42)

The presence of aggregated amyloid-β peptides (Aβ) is one of the hallmarks of Alzheimer's Disease (AD). However, the form(s) of Aβ-peptides that are associated with this pathology remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal amyloid precursor protein (APP) and not Aβ exclusively.

 

Our Biosensis MOAB-2 antibody (M-1586-100) is a new pan-specific monoclonal antibody to Amyloid beta residues 1-4 and provides unparalleled staining clarity, stronger reactivity and greater sensitivity than any other Abeta monoclonal antibodies previously available for research. Also, unlike other monoclonals such as 6E10 and 4G8, MOAB-2 does not cross react with APP or APP C-terminal fragments.

 

The Biosensis formulation of MOAB-2 is also the only one endorsed by the original developers.

 

Biosensis MOAB-2 antibody to Amyloid beta peptide (A beta 40/42)

 

Related products:

Biosensis APP antibodies, Oligomeric Amyloid-beta ELISA Kits,

Amylo-Glo - Amyloid beta plaque staining solution

 



NEW: Active Tau Monomers and Preformed Fibrils 
 

New Active Tau Proteins available as monomers and preformed fibrils (PFFs):

 

From a full-length tau protein (2N4R/Tau-441) with a P301S mutation encoded by exon 10 to prevent microtubule assembly.

Active Human Recombinant Tau441 (2N4R), P301S Protein Monomer (SPR-327)

Active Human Recombinant Tau441 (2N4R), P301S Protein Pre-formed fibrils (SPR-329)

 

Or from a truncated form of human tau (K18) containing only the 4 microtubule binding repeats with a P301L (PL) mutation that promotes beta-sheet formation and the formation of PHFs.

Active Human Recombinant Tau (K18), P301L Protein Monomer (SPR-328)

Active Human Recombinant Tau (K18), P301L Protein Pre-formed fibrils (SPR-330)

 

Active Tau Preformed Fibrils

 

Newmarket Scientific Blog: (Tau Aggregation and Propagation - Alzheimer's Disease)

 


 

NEW: Active Alpha Synuclein Proteins 

 

Alpha Synuclein proteins involved in Lewy Body pathology.

Active Human Recombinant Alpha Synuclein Protein Aggregate (SPR-322/SPR-317)

Active Human Recombinant Alpha Synuclein Protein Monomer (SPR-321/SPR-316)

 

Active Mouse Recombinant Alpha Synuclein Monomer and Aggregate (SPR-323/SPR324)

 

Alpha-Synuclein-preformed fibrils

 

Newmarket Scientific Blog: (First Commercially Available Active Human and Mouse ASYN Proteins)

 



Neurodegenerative Disease Research

 

Agrisera's neuroscience range includes antibodies for use in Alzheimer's disease research (Beta Amyloid antibodies), and Parkinson's disease (Alpha-synuclein)

 

Also available is our DNA Damage ELISA which allows the user to quantify oxidative damage of DNA by measuring 8-OHdG levels.

 

For further information follow the links above or alternatively complete our contact form.

Agrisera   neuroscience

 



Neuroscience - ImmunoStar

 

Newmarket Scientific is the UK and Ireland Distributor for the ImmunoStar range of antibodies for neuroscience research.

 

This range of primary antibodies was originally provided by DiaSorin (formerly INCSTAR), but in 2001 the range became Immunostar. As these antibodies have been available for many years there are multiple references citing their use.

 

Additionally ImmunoStar antibodies are put through extensive testing before release to ensure both high quality and high titer. This provides excellent reliability and lot-to-lot consistency. These antibodies have also been specifically tested for use in immunohistochemistry. 

 

Immunostar neuroscience

Details of the full range of 60+ well referenced neuroscience antibodies are available on this link.