Newmarket Scientific
Newmarket Scientific








Exosomics


Isolation and enrichment of tumour-originated extracellular vesicles and exosomes


Exosomics - Solutions for extracellular vesicle  isolation

The exosomics range provides solutions for the isolation and selective enrichment of tumour-originating extracellular vesicles (EVs) and exosomes from complex biofluids, providing researchers invaluable solutions to detect early cancer hallmarks.

 

It also includes the ExoRef™ exosome based reference standards which contain cancer relevant mutations which help in monitoring the performance of exosome based cancer diagnostic workflow from plasma to result.

 


 


NEWS: Tumour-derived RNA and DNA purification

Exosomics - Solutions for extracellular vesicle  isolation

SeleCTEV-DNA and SoRTEV-RNA for tumour derived DNA and RNA purification

 

Current liquid biopsy methods generally isolate total nucleic acids from blood but with only low levels of tumour-derived RNA and DNA. However the Exosomics SeleCTEV-DNA and SoRTEV-RNA kits allow the isolation of tumour-derived genetic material without the need for special equipment, such as ultracentrifugation or chromatography. Using unique proprietary affinity methods these kits selectively purify tumour-derived extracellular vesicles and exosomes from which RNA and DNA can then be extracted.

 

Purification of tumour-originating nucleic acids from tumour enriched EVs and exosomes

 

SoRTEV™ EV-RNA Low Volume (24 rxns)

This kit allows the purification of tumour derived RNA from tumour enriched exosomes in biofluids and includes a user-friendly protocol for RNA purification. The exosome purification is based on immune-affinity beads coated with proprietary antibodies against exosome surface antigens.

SoRTEV

 

SeleCTEV™ EV-DNA Low Volume (24rxn)

This kit allows the purification of both circulating free DNA (cfDNA) and tumour-derived exosome DNA from plasma and/or serum with a starting volume of 0.5 to 2ml. The purification is based on Exosomics proprietary peptide affinity method and this kit includes a user-friendly protocol for DNA purification.

 

SeleCTEV-HV