Newmarket Scientific Product Search Results for rnl2

Product Search Results: rnl2
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Product Search Results: rnl2	Num Products Matched: 2	2

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Monosan

MON2096

100 ug

£388.00

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Product Detail:	Mouse anti-NSP-A and NSP-B, clone RNL-3, Purified (Monoclonal)
Antibody Type:	Monoclonal
Host Animal:	Mouse
Species Reactivity:	human, monkey, rabbit
Immunogen:	small cell lung cancer cell line NCI-H82
Applications:	FC (1:100-1:200), ICC, IHC-fr (1:100), IHC-p (1:100), WB (1:100-1:500)
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82. Reticulon-1B is sofar not found in Human tissues. Reticulon-1C is a protein with a MW of 23 kDa which is not phosphorylated and is found with Reticulon-1A in SCLC (cell lines) and not in non-SCLC (cell cultures).RNL-2 recognizes an epitope located within the region of amino acids 421-589 of the neuro-endocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B). In normal tissues, RNL-2 reacts with brain Purkinje cells, pancreatic islet cells, cells in the pituitary gland and some (peripheral) nerve fibers. In addition, a few epithelia show positive staining.
Antibody Isotype:	IgG1
Monosan Range:	MONOSAN
Clone:	RNL-3
Concentration:	1 mg/ml
Storage buffer:	PBS with 0.09% sodium azide
Storage:	2-8°C
References 1:	Broers et al. Cancer 1991;67:619-633
References 2:	Roebroek et al. J Biol Chem 1993;268:13439-47
References 3:	Senden et al. Int J Cancer Suppl 1994;8:84-8
References 4:	Senden et al. Eur J Cell Biol 1996;69:197-213
References 5:	Senden et al. J Pathol 1997;182:13-21

Monosan

MON2095

100 ug

£388.00

Please sign in or sign up to order this product online.

Product Detail:	Mouse anti-NSP-A and NSP-B, clone RNL-2, Purified (Monoclonal)
Antibody Type:	Monoclonal
Host Animal:	Mouse
Species Reactivity:	human, monkey, rabbit
Immunogen:	small cell lung cancer cell line NCI-H82
Applications:	FC (1:25-1:100), ICC, IHC-fr (1:50), IHC-p (1:50), WB (1:100-1:1000)
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82. Reticulon-1B is sofar not found in Human tissues. Reticulon-1C is a protein with a MW of 23 kDa which is not phosphorylated and is found with Reticulon-1A in SCLC (cell lines) and not in non-SCLC (cell cultures).RNL-2 recognizes an epitope located within the region of amino acids 421-589 of the neuro-endocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B). In normal tissues, RNL-2 reacts with brain Purkinje cells, pancreatic islet cells, cells in the pituitary gland and some (peripheral) nerve fibers. In addition, a few epithelia show positive staining.
Antibody Isotype:	IgG1
Monosan Range:	MONOSAN
Clone:	RNL-2
Concentration:	1 mg/ml
Storage buffer:	PBS with 0.09% sodium azide
Storage:	2-8°C
References 1:	Broers et al. Cancer 1991;67:619-633
References 2:	Roebroek et al. J Biol Chem 1993;268:13439-47
References 3:	Senden et al. Int J Cancer Suppl 1994;8:84-8
References 4:	Senden et al. Eur J Cell Biol 1996;69:197-213
References 5:	Senden et al. J Pathol 1997;182:13-21

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