Kits and Assays

Newmarket Scientific provides a range of assays covering:

• Apoptosis
Protein Detection and Reporter Assays
and our In-Cell ELISA
• Gene-specific Cytokine ELISAs

• Detection of Microbial and Industrial contaminants and Natural toxins
• Dairy Testing
• Melamine

• Preclinical Toxicity Testing Assays
• Forensic Drug Detection
• Drug residues

Please use the search above to find the product you are looking for or if you are having difficulty locating it, simply use our contact form and we'll look for you or e-mail us at tech@nktscientific.com.

Caspase-3 is a ubiquitously-expressed cysteine protease involved in programmed cell death (apoptosis). In nonapoptotic cells, this enzyme exists as an inactive zymogen known as procaspase-3. Intracellular procaspase-3 is activated when cells are committed to die via apoptosis; induction of the cell death machinery eventually triggers activation of the zymogen by proteolytic cleavage of the zymogen to an active heterodimer comprised of 17 kDa and 12 kDa subunits.

The active enzyme cleaves a number of intracellular protein targets important for cell survival. Therefore, monitoring caspase-3 enzyme activity is a fundamental means to measure apoptosis in cells. This assay is an important tool for apoptosis research as well as investigating the apoptotic effects of experimental drug formulations and cell transfection.

The MaxDiscovery™ Caspase-3 Fluorescence Detection Kit is a fluorescence microplate-based assay to directly measure caspase-3 activation in cultured cells. This kit enables biomedical researchers to determine caspase-3 levels in cultured cells from a broad range of cell lines. The assay utilizes a simple, proven enzymatic assay to detect activated enzyme.

The MaxDiscovery™ Caspase-3 Colormetric Detection Kit is a colorimetric microplate-based assay to directly measure caspase-3 activation in cultured cells. This kit enables biomedical researchers to determine caspase-3 levels in cultured cells from a broad range of cell lines. The assay utilizes a simple, proven enzymatic assay to detect activated enzyme.

Both kits offer:

• High sensitivity
• High compatibility across a broad range of cell lines
• A robust enzyme-based assay which does not require expensive instrumentation
• High reproducibility

If you have any questions regarding these kits simply email us at tech@nktscientific.com or complete our contact form on this link.

Newmarket Scientific are also able to provide custom Sera and Plasma formulated to your specific requirements.

Standard species include:

• Human
• Mouse (male/female, Balb-C, Swiss, C57 and CD1 and most other species)
• Rat (male/female, SD, Wistar or Fisher 344)
• Rabbit
• Goat
• Bovine
• Canine
• Guinea Pig
• Horse
• Monkey (Rhesus and Cynomologus)
• Sheep
• Syrian Hamster
• Swine (Pig)
• Chicken
• Duck
• Plus other species may be available on request. 

Anti-coagulants available for plasma include EDTA, Na citrate, and heparin (Na, K and lithium).

To request a quotation or ask questions regarding your specific requirements please email tech@nktscientific.com or complete our contact form.